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Posted on Wednesday, June 12, 2019 by Shayne Foley, PA-C

Lyme Disease: What You Need to Know


Shayne Foley, PA-C is a physician assistant at CVMC Family Medicine - Mad River.

In my 7 years of experience as a Physician Assistant, I’ve diagnosed and treated an increasing amount of Lyme disease, and with this increase, the concerns regarding it are also rising, sometimes disproportionately. The goal of this post is to provide the readers with evidence-based information that I hope will serve our community to better understand Lyme disease.

Lyme Disease in Vermont – The Facts

According to the Vermont Department of Health (VDH), there were 1,092 confirmed or probable causes of Lyme disease in Vermont in 2017, the most recent year when statistics are available. The number of cases of Lyme disease in Vermont has been steadily climbing over the last few decades, the reasons for which are multi-factorial.

The majority of cases were reported from the southern part of Vermont, with Washington County reporting Lyme disease at a rate of a little less than 1 in every 1,200 residents.

About Lyme Disease

Lyme disease is the most common tick-borne disease in the United States. It is caused by the bacteria Borrelia burgdorferi, which is carried and transmitted by the blacklegged tick, more commonly known as the “deer tick.”

According to the VDH, over half of the deer ticks they studied tested positive for Lyme disease. Bites occur most commonly in the late spring and summer, but can occur during other seasons also. Once bitten, the process of Lyme disease transmission requires the deer tick to be attached to the skin for at least 48-72 hours. Without the tick being engorged (filled with blood), usually less than 36-48 hours of attachment, there is an estimated 99 percent chance of NOT acquiring Lyme disease if the deer tick is removed promptly. Ticks that have not embedded into the skin cannot transmit Lyme or other tick-borne illnesses.

Phases of Lyme Disease

There are multiple phases of Lyme disease, which include:

  • early localized (note: I will be focusing primarily on early localized in this article)
  • early disseminated, and
  • late disease.

During the early localized phase, signs and symptoms of Lyme disease commonly occur within one month of a tick bite, and include:

  • rash,
  • fever,
  • swollen glands,
  • muscle and joint aches, joint swelling and/or redness,
  • headaches,
  • neck stiffness. and
  • generalized fatigue or sense of not feeling well.

The Erythema Migrans Rash is present in approximately 80 percent of cases.

Erythema Migrans Rash is present in approximately 80 percent of cases.

The most well known symptom of Lyme disease seems to be the Erythema Migrans rash, often referred to as a “bull’s-eye” due to the appearance. Approximately 80 percent of people with Lyme disease will develop this rash, but in the majority of cases, it will not have that classic “bull’s-eye” appearance, and may be confused with other non-descript rashes. The other symptoms can also be rather non-specific, so it is best to see a healthcare provider if you develop the symptoms consistent with Lyme disease.

How Lyme Disease Is Diagnosed

The diagnosis of Lyme disease can be made in a variety of ways, including clinically or through laboratory testing.

Clinical Diagnosis: To diagnose clinically means based on your symptoms and physical exam findings alone, without testing. If you are found to have classic features of Lyme disease, such as the Erythema Migrans rash, chances are that treatment can start without any testing.

Laboratory Testing: Blood testing is less reliable in the first several weeks after a known or suspected tick bite. According to UpToDate, “virtually everyone with Lyme disease has a positive test result” as the infection progresses. Blood testing typically includes the ELISA test, which has been shown to be very good at detecting antibodies to Lyme disease, and the Western Blot, which is typically used if the ELISA is not clearly positive or negative. (Note: In the lab at CVMC, the ELISA is used for screening and the Western Blot is used for confirmation as part of a 2-step testing algorithm.)

Testing the tick for Lyme disease or other illnesses is not recommended, as it may delay diagnosis and treatment. A healthcare practitioner can help to explain these tests in greater detail and determine if they may be of benefit to you.

Treatment of Lyme Disease

If the determination has been made to treat confirmed or suspected Lyme disease, antibiotics are a very effective treatment in all stages of the disease. The antibiotics that are effective for Lyme disease are Doxycycline, Amoxicillin and Cefuroxime axetil.

Doxycycline is the preferred treatment, given that it has excellent efficacy in treating Lyme disease, no suspected antibiotic resistance, as well as that it treats some other tick-borne illnesses as well. It can also be used as a prophylaxis, or preventative treatment strategy, should a person meet ALL of the criteria below, according to the Infectious Diseases Society of America (IDSA):

  1. The attached tick is definitely identified as a deer tick
  2. The tick is estimated to have been attached for ≥36 hours
  3. The antibiotic (Doxycycline) can be given within 72 hours of tick removal
  4. The person bitten can take Doxycycline (this is the only antibiotic approved for prophylaxis)
  5. The local rate of tick infection with B. burgdorferi is ≥20 percent

If you meet the criteria above, a healthcare provider should see you, as you are potentially a candidate for a shorter, prophylactic dose of Doxycycline. If you are not positive whether a deer tick bit you, it is helpful to bring along the offending tick for identification.

Prevention Is Still the Best Way to Avoid Lyme Disease

Although there is a good prognosis for those people treated for Lyme disease, the best method of treatment is still prevention.

Prevention can be best accomplished by following these precautions:

  • avoiding areas with high grass and leaf litter,
  • minimizing skin exposure with long pants and long-sleeved shirts,
  • tucking your pants into your socks,
  • wearing light-colored clothing to easily spot ticks, and
  • using effective and safe tick repellents (some repellents are not safe for certain populations, so please do some research or speak with a healthcare provider or pharmacist before purchasing).

Other preventative strategies include:

  • doing tick checks on yourself and others immediately upon returning from an area suspected of or known to have tick populations,
  • showering within a few hours of being indoors, and
  • putting your worn clothing in a dryer on high heat for 10 minutes to kill any ticks present.

With skin checks, pay special attention to the scalp, neck, ears, back, underarms, belly button, waist, hips, pelvic area, groin, as well as behind the knees.

Should prevention not be enough and you get a tick bite, I recommend taking the following steps:

  1. Remove the tick with fine-tipped tweezers.
  2. Place the tick in an enclosed container.
  3. Attempt to identify if the tick is a deer tick.
  4. If it is a deer tick and has been present for more than 36 hours, see a healthcare provider within 72 hours of tick removal.

What to Do If You Think You Have Signs or Symptoms of Lyme Disease

If you are displaying signs and symptoms of Lyme disease as listed above, even without a known tick bite, seek out a healthcare provider.

Not everyone displaying symptoms has a known tick bite, but keep in mind that not everyone with symptoms also has Lyme disease. It is best to discuss this during your visit with a healthcare provider.

It’s inevitable now that I will encounter at least one patient per shift who has come in with a tick bite and concern for Lyme disease. This comes as no surprise with the increasing presence of ticks and how us Vermonters tend to be outdoorsy. As we don’t want these tiny creatures to change our lifestyle, I strongly recommend taking precautions and using preventative strategies to avoid tick bites and the potential for Lyme disease. If, despite prevention, you are still bit by a deer tick or just displaying symptoms of Lyme disease, please use reputable resources such as the Center for Disease Control, Vermont Department of Health, healthcare providers and this article to help determine the appropriate course of action.


  1. Center for Disease Controlhttps://www.cdc.gov/lyme/index.html
  2. UpToDate
    “Patient education: Lyme disease symptoms and diagnosis (Beyond the Basics)”
    “Patient education: What to do after a tick bite to prevent Lyme disease (Beyond the Basics)”
    “Treatment of Lyme disease”
  3. Vermont Department of Healthhttp://www.healthvermont.gov/disease-control/tickborne-diseases/lyme-disease
    “Ticks and the Disease They Spread in Vermont” handout